Comparing Emisphere Technologies (OTCMKTS:EMIS) and Cytokinetics (OTCMKTS:CYTK)

Cytokinetics (NASDAQ:CYTK) and Emisphere Technologies (OTCMKTS:EMIS) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their risk, profitability, dividends, institutional ownership, valuation, analyst recommendations and earnings.

Insider and Institutional Ownership

69.3% of Cytokinetics shares are owned by institutional investors. Comparatively, 0.0% of Emisphere Technologies shares are owned by institutional investors. 5.7% of Cytokinetics shares are owned by company insiders. Comparatively, 72.9% of Emisphere Technologies shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Analyst Ratings

This is a breakdown of recent recommendations and price targets for Cytokinetics and Emisphere Technologies, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cytokinetics 0 1 3 0 2.75
Emisphere Technologies 0 0 0 0 N/A

Cytokinetics presently has a consensus target price of $15.75, suggesting a potential upside of 66.67%. Given Cytokinetics’ higher probable upside, equities research analysts clearly believe Cytokinetics is more favorable than Emisphere Technologies.

Earnings & Valuation

This table compares Cytokinetics and Emisphere Technologies’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Cytokinetics $31.50 million 17.32 -$106.29 million ($1.95) -4.85
Emisphere Technologies $1.20 million 717.48 -$10.04 million N/A N/A

Emisphere Technologies has lower revenue, but higher earnings than Cytokinetics.

Profitability

This table compares Cytokinetics and Emisphere Technologies’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Cytokinetics -303.70% -269.27% -47.50%
Emisphere Technologies N/A N/A N/A

Volatility & Risk

Cytokinetics has a beta of 1.71, indicating that its share price is 71% more volatile than the S&P 500. Comparatively, Emisphere Technologies has a beta of 2.14, indicating that its share price is 114% more volatile than the S&P 500.

Summary

Emisphere Technologies beats Cytokinetics on 7 of the 11 factors compared between the two stocks.

About Cytokinetics

Cytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised and/or declining. The company is developing small molecule drug candidates primarily engineered to increase muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure; and reldesemtiv, a novel fast skeletal muscle troponin activator, which is in Phase II clinical trial to treat amyotrophic lateral sclerosis and spinal muscular atrophy. The company also develops reldesemtiv that is in Phase II clinical trials in patients with chronic obstructive pulmonary disease, as well as in Phase Ib clinical trials in elderly subjects with limited mobility. In addition, it develops CK-3773274, a novel cardiac myosin inhibitor, which is in Phase I clinical trial for the potential treatment of hypertrophic cardiomyopathy; and AMG 594, a novel cardiac troponin activator that is in Phase I clinical trial. The company has strategic alliances with Amgen Inc. and Astellas Pharma Inc. Cytokinetics, Incorporated was founded in 1997 and is headquartered in South San Francisco, California.

About Emisphere Technologies

Emisphere Technologies, Inc. operates as a commercial stage pharmaceutical and drug delivery company in the United States. The company offers oral Eligen B12 Rx, an oral formulation prescription medical food for use by B12 deficient individuals. It is also developing GLP-1, which is in Phase III clinical trial for the treatment of type 2 diabetes and related conditions. The company's preclinical programs focus on the development of oral formulations for the treatment of diabetes; and products in the areas of cardiovascular, appetite suppression, and pain, as well as in the development and expansion of nutritional supplement products. It has license agreements with Novo Nordisk A/S to develop and commercialize oral formulations of GLP-1 receptor agonists in combination with Emisphere carriers, as well as to develop and commercialize oral formulations of Novo Nordisk's insulin using the company's Eligen Technology. The company was formerly known as Clinical Technologies Associates, Inc. and changed its name to Emisphere Technologies, Inc. in 1991. Emisphere Technologies, Inc. was founded in 1986 and is based in Roseland, New Jersey.

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